Timothy Daltonas Sir Malcolm Murray
Eva Greenas Vanessa Ives
Harry Treadawayas Dr. Victor Frankenstein
Josh Hartnettas Ethan Chandler
Rory Kinnearas The Creature
Billie Piperas Brona Croft / Lily
Reeve Carneyas Dorian Gray
Danny Sapanias Sembene
Simon Russell Bealeas Ferdinand Lyle
Helen McCroryas Evelyn Poole
Patti LuPoneas Dr. Seward
